However, when you are comparing Pill Boxes with Compartments to Single Compartment Pill Boxes, go ahead and figure out your medication and lifestyle and oral medication seems to be a good option, take these into consideration. Persons with multiple prescriptions will find Pill Boxes with Compartments Printed Lid useful, but those with only a couple of more simple needs may get by with Single Compartment Pill Box. Ultimately, it all comes down to how complex and complicated your medication needs are.